Orthosiphon
 Cat's Whiskers - Java tea
diuretic  -

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Cat's Whiskers Tea

OTOP Cat's Whiskers Tea

Orthosiphon grandiflorus

KLO Compound Orthosiphon  Extract - Cat's Whiskers
100 Tablets

€ 9.00

PN Compound Orthosiphon Extract - Cat's Whiskers
100 capsules

€ 6.00

TP Compound Orthosiphon
Cat's Whiskers
100 capsules
€ 6.00

Compound Orthosiphon
grandiflorus
100 tablets

PN Cat's Whiskers
100 capsules

TP Cat's Whiskers
100 capsules
Directions
1 - 2 tablets, 2 to 3 times a day
Directions
1-3 tablets, 3 times a day after meals
Directions
3 capsules twice a day after meals
 

Uses and Properties:
Java tea is mainly used as a diuretic in cases of chronic inflammation of the kidney and bladder and in gall bladder catarrh, kidney catarrh, bacteriuria and irritable bladder. The product is used on its own or in combination with tea mixtures and urological preparations.

The Diverse Benefits of a Unique Natural Diuretic

By VRP Staff

A diuretic is any substance that increases urination rate and therefore increases the excretion of water. Diuretics are often used clinically along with blood pressure medications in order to flush excess fluid and sodium from the body to decrease the amount of fluid pumped by the heart. Furthermore, diuretics are also used to reduce bloating and fluid retention. These effects make diuretics useful for individuals who are undergoing weight loss and for women who want to reduce the fluid build up that occurs during PMS. Diuretics also may be indicated in kidney stones and gout.

Orthosiphon stamineus, otherwise known as java tea, has been used in traditional medicine for centuries to enhance the health of the urinary system. Orthosiphon stamineus is a popular traditional botanical extensively used in Southeast Asia for a wide range of conditions including rheumatism, diabetes, hypertension, tonsillitis, epilepsy, menstrual disorders, gonorrhea, syphilis, renal calculus (kidney stones), gallstones, edema, eruptive fever, hepatitis, and jaundice.1 In Japan, it is consumed as a healthy tea to facilitate body detoxification.1

Research confirms the traditional role of this botanical with studies showing it has diuretic properties. Rodent studies have indicated supplementation with Orthosiphon stamineus leads to an increase in urine flow and increased urinary sodium excretion.2These properties indicate Orthosiphon stamineus can play a role in kidney health, but its effects appear to expand to other aspects as well.

Kidney Stones and Gout

Calcium oxalate stones are the most common type of kidney stones, which can be detected by routine x-ray studies. This type of stone is unlikely to be treated successfully with medical therapy but certain medications may help prevent calcium stones if they have a propensity to recur.

Kidney stones can also be caused by disordered uric acid metabolism. Uric acid is a common constituent of urinary and renal calculi (kidney stones) and of gouty concretions. Diuretic action is an important factor in treatment of kidney stones of this type. An increase in the volume of fluid flowing through the kidney will help to dissolve the stones, assisting their passing to avoid further retention, and flushing out the deposits.

Two recent studies provide a scientific foundation for the traditional use of Orthosiphon stamineus in kidney stones and gout. First, Orthosiphon stamineus appears to influence the activity of adenosine A (1) receptor antagonists, which can protect the kidney by increasing urine flow and sodium excretion.3

Additionally, an earlier study showed that Orthosiphon stamineus lowered levels of uric acid in rodents and acted as a diuretic.4

Fever Reduction

A recent study indicates another interesting property of Orthosiphon stamineus. Researchers experimentally elevated body temperature in rodents then gave them Orthosiphon stamineus. The botanical significantly reduced the increased body temperature. The effect persisted up to four hours following the administration of the extract. Orthosiphon stamineus’ anti-pyretic (fever-reducing) effect was comparable with that of acetaminophen.5

Anti-inflammatory and Analgesic Effects

Researchers also have studied Orthosiphon stamineus for its effects on inflammation and pain. Scientists induced edema in the hind paws of rodents. They then gave the animals Orthosiphon stamineus. The botanical significantly reduced the edema 3 and 5 hours after the swelling was induced. Furthermore, Orthosiphon stamineus also produced significant analgesic (pain-reducing) activity.6

According to the researchers, “The results of the present study support the proposal that O. stamineus has anti-inflammatory and non-narcotic analgesic activities. These findings justify the traditional use of the plant for treating pain and inflammation.”

Liver Health

A 2007 study suggests that Orthosiphon stamineus may be as protective to the liver as it is to the kidney. Researchers treated rats with Orthosiphon stamineus then induced liver toxicity in the rodents. The botanical dose-dependently reduced the necrotic changes in the liver and inhibited the increase of serum ALT and AST activities. Orthosiphon stamineus also acted as a powerful antioxidant and free radical scavenger.7

Maintaining Blood Sugar

Unlike some pharmaceutical diuretics, which are thought to increase the risk of diabetes by promoting glucose intolerance,Orthosiphon stamineus can actually maintain blood sugar levels. When the extract was given to normal and diabetic rats, it significantly decreased plasma glucose concentration in a dose-dependent manner. After repeated daily oral administrations of the extract for 14 days, the extract significantly reduced plasma glucose concentration in diabetic rats at days 7 and 14. By the end of the study, plasma triglyceride concentration was lower in the extract-treated diabetic rats than untreated ones. Furthermore, plasma HDL-cholesterol concentration was significantly increased in diabetic rats treated with the extract.8

“Our findings suggested that Ortho­siphon stamineus aqueous extract is effective for alleviating hyperglycemia and improving lipid profile in diabetic rats,” the researchers wrote.

Balancing Nitric Oxide Levels

Nitric oxide (NO) is an important molecule that signals the blood vessels to relax and acts in many tissues to regulate a diverse range of physiological processes. When certain cells are activated by specific proinflammatory agents such as endotoxins, tumor necrosis factor (TNF), interferon-gamma (IFN-g), and interleukin-1 (IL-1), NO is produced and protects the host by damaging pathogenic DNA. Balanced amounts of nitric oxide are essential to optimal health because just as normal amounts of NO promote health, the excessive production of NO that can occur during the inflammatory process can have detrimental effects on many organ systems of the body, which can lead to tissue damage. Therefore, inhibiting NO accumulation by inflammatory stimuli can result in overall benefits.

Orthosiphon stamineus has been shown to inhibit levels of nitric oxide in macrophages that were stimulated with inflammatory endotoxins, indicating that the botanical can help support healthy levels of nitric oxide and reduce one of the harmful effects of inflammation.1

Safety of Orthosiphon stamineus

The diuretic botanical Orthosiphon stamineus has been extensively studied in rodents with no signs of toxicity. In a 2008 study, researchers administered the botanical orally to rats for 14 days and compared it to a control group receiving distilled water. The four test groups were treated with 0.5 g/kg, 1 g/kg, 3 g/kg and 5 g/kg body weight of O. stamineus respectively. No lethality or adverse toxic signs were seen during the experimental period.9

According to the researchers, “In conclusion, methanol extract of O. stamineus within these range and treatment duration would not cause any severe toxic effects and organ damage in rats.”

Individuals in Malaysia, Vietnam and Japan have consumed Orthosiphon stamineus for centuries, further supporting its safety.

Conclusion

Orthosiphon stamineus, which is found in the new product Herbal Diuretic along with 99 mg of potassium, is a natural diuretic supplement that can support kidney and liver health, reduce the excessive fluid retention that occurs during PMS, alleviate bloating, promote sodium excretion and act as an anti-inflammatory and analgesic agent. For individuals seeking diuretic support, it is an excellent choice that can also maintain liver health and blood sugar.

References

1. Awale S, Tezuka Y, Banskota AH, Siphonols KS. Novel Nitric Oxide Inhibitors from Orthosiphon stamineus of Indonesia. Bioorganic & Medicinal Chemistry Letters. 2003;13:31–35.

2. Beaux D, Fleurentin J, Mortier F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother Res. 1999 May;13(3):222-5.

3. .Yuliana ND, Khatib A, Link-Struensee AM, Ijzerman AP, Rungkat-Zakaria F, Choi YH, Verpoorte R. Adenosine A1 receptor binding activity of methoxy flavonoids from Orthosiphon stamineus. Planta Med. 2009 Feb;75(2):132-6.

4. Arafat OM, Tham SY, Sadikun A, Zhari I, Haughton PJ, Asmawi MZ. Studies on diuretic and hypouricemic effects of Orthosiphon stamineus methanol extracts in rats. J Ethnopharmacol. 2008 Aug 13;118(3):354-60.

5. Yam MF, Ang LF, Basir R, Salman IM, Ameer OZ, Asmawi MZ. Evaluation of the anti-pyretic potential of Orthosiphon stamineus Benth standardized extract. Inflammopharmacology. 2009 Feb;17(1):50-4.

6. Yam MF, Asmawi MZ, Basir R. An investigation of the anti-inflammatory and analgesic effects of Orthosiphon stamineus leaf extract. J Med Food. 2008. Jun;11(2):362-8.

7. Yam MF, Basir R, Asmawi MZ, Ismail Z. Antioxidant and hepatoprotective effects of Orthosiphon stamineus Benth. standardized extract. Am J Chin Med. 2007;35(1):115-26.

8. Sriplang K, Adisakwattana S, Rungsipipat A, Yibchok-Anun S. Effects of Orthosiphon stamineus aqueous extract on plasma glucose concentration and lipid profile in normal and streptozotocin-induced diabetic rats. J Ethnopharmacol. 2007 Feb 12;109(3):510-4.

9. Chin JH, Abas HH, Sabariah I. Toxicity study of Orthosiphon stamineus Benth (Misai Kucing) on Sprague Dawley rats. Trop Biomed. 2008 Apr;25(1):9-16.